The most important causes of oxidative stress and its impact on cardiovascular diseases

Abstract

The increase in oxidative stress that contributes to CVD is one of the most common causative factors, aggravating symptoms and resulting in serious harm. This study aimed to investigate different biomarkers of oxidative stress in patients with CVD and the biochemical parameters related to these disorders. Participants Methods the research included 56 participants aged between 30 and 65 years, with 28 patients in each group, to be treated as follows: the first group consisted of patients diagnosed with CVD (Group I) and the second was considered healthy (control Group II). Thus, in this study, we demonstrate that oxidative stress and inflammation are intimately connected with CVD. The mitochondrial processes that mediate this relationship will also be presented, as well as the different strategies to circumvent redox/inflammatory biological effects. With regards to each individual from the three groups, these indicators and parameters malondialdehyde (MDA), 8-hydroxydeoxyguanosine (8-OHdG), albumin, uric acid, urea and creatinine.